2251709-89-2
2251709-89-2
Chemical Structure
PLK1/BRD4-IN-2
- CAS No.: 2251709-89-2
- Formula:C27H36N6O3
- Molecular Weight:492.61
InChIKey: WHCFLSAKSTZDQY-GOSISDBHSA-N
SMILES: C[C@H]1N(C2CCCC2)C3=NC(NC4=C(C=C(C=C4)C(N5CCCCCC5)=O)OC)=NC=C3N(C1=O)C
Biological Activity: PLK1/BRD4-IN-2 (compound 15) is a BI-2536 (HY-50698) analog and dual inhibitor that targets both Polo-like kinase 1 (PLK1) and BRD4bromodomain (BRD4-BD1 IC50=28 nM, PLK1 IC50=40 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PLK1/BRD4-IN-2 | 98.92% | PLK1/BRD4-IN-2 (compound 15) is a BI-2536 (HY-50698) analog and dual inhibitor that targets both Polo-like kinase 1 (PLK1) and BRD4bromodomain (BRD4-BD1 IC50=28 nM, PLK1 IC50=40 nM). | ||||||||||||||||||||
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References
Keywords
