2253635-71-9
2253635-71-9
Chemical Structure
Antileishmanial agent-11
- CAS. Nr.: 2253635-71-9
- Formula:C27H24ClN3O4
- Molecular Weight:489.95
IUPAC Name: 3-(3-methylbut-2-en-1-yl)-1,4-dioxo-1,4-dihydronaphthalen-2-yl 4-(1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)butanoate
InChIKey: RKHHAANAPIAQJB-UHFFFAOYSA-N
SMILES: O=C(OC(C1=O)=C(C/C=C(C)\C)C(C2=C1C=CC=C2)=O)CCCC3=CN(C4=CC=C(Cl)C=C4)N=N3
Biological Activity: Antileishmanial agent-11 (compound 4d) is a potent anti-leishmanial agent. Antileishmanial agent-11 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 28.3, 24.8 and 13.0 μM, respectively[1].
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Antileishmanial agent-11 | Antileishmanial agent-11 (compound 4d) is a potent anti-leishmanial agent. Antileishmanial agent-11 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 28.3, 24.8 and 13.0 μM, respectively. | |||||||||||||||||||||
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