2259648-80-9

Mezigdomide Chemical Structure
2259648-80-9

Chemical Structure

Mezigdomide

Synonym(s): CC-92480

  • CAS No.: 2259648-80-9
  • Formula:C32H30FN5O4
  • Molecular Weight:567.61

IUPAC Name: (S)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile

InChIKey: YTINZZFBHWSAGL-NDEPHWFRSA-N

SMILES: N#CC1=CC=C(N2CCN(CC3=CC=C(COC4=CC=CC5=C4CN([C@@H](CC6)C(NC6=O)=O)C5=O)C=C3)CC2)C(F)=C1

Biological Activity: Mezigdomide (CC-92480), a cereblon E3 ubiquitin ligase modulating agent (CELMoD), acts as a molecular glue. Mezigdomide shows high affinity to cereblon, resulting in potent antimyeloma activity[1].

Cat. No. Product Name Purity Description Pricing
HY-129395
Mezigdomide 99.81% Mezigdomide (CC-92480), a cereblon E3 ubiquitin ligase modulating agent (CELMoD), acts as a molecular glue. Mezigdomide shows high affinity to cereblon, resulting in potent antimyeloma activity.
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