22644-96-8
Chemical Structure
(E)-2-Hexadecenal
Synonym(s): 16:1 Aldehyde; trans-2-Hexadecenal
- CAS No.: 22644-96-8
- Formula:C16H30O
- Molecular Weight:238.41
IUPAC Name: (E)-hexadec-2-enal
InChIKey: KLJFYXOVGVXZKT-CCEZHUSRSA-N
SMILES: CCCCCCCCCCCCC/C=C/C=O
Biological Activity: (E)-2-Hexadecenal (trans-2-Hexadecenal) is an MLK3 activator that induces cytoskeletal remodeling, leading to cell rounding, detachment, and ultimately apoptosis in human and mouse cells. (E)-2-Hexadecenal activates the MLK3 signaling pathway, phosphorylating MKK4/7 and JNK, subsequently activating downstream targets of JNK, such as c-Jun phosphorylation, cytochrome c release, Bax activation, Bid cleavage, and Bim translocation to mitochondria. (E)-2-Hexadecenal has potential applications in research related to sphingolipid signaling pathways[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(E)-2-Hexadecenal | 99.9% | (E)-2-Hexadecenal (trans-2-Hexadecenal) is an MLK3 activator that induces cytoskeletal remodeling, leading to cell rounding, detachment, and ultimately apoptosis in human and mouse cells. (E)-2-Hexadecenal activates the MLK3 signaling pathway, phosphorylating MKK4/7 and JNK, subsequently activating downstream targets of JNK, such as c-Jun phosphorylation, cytochrome c release, Bax activation, Bid cleavage, and Bim translocation to mitochondria. (E)-2-Hexadecenal has potential applications in research related to sphingolipid signaling pathways. | ||||||||||||||||||||
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