2276711-87-4
Chemical Structure
Xanthine oxidase-IN-5
- CAS No.: 2276711-87-4
- Formula:C18H16FN3O3
- Molecular Weight:341.34
IUPAC Name: 5-fluoro-2-((1-(3-methoxybenzyl)-1H-1,2,3-triazol-4-yl)methoxy)benzaldehyde
InChIKey: CYKGEFAYEZMOJC-UHFFFAOYSA-N
SMILES: O=CC1=CC(F)=CC=C1OCC2=CN(CC3=CC=CC(OC)=C3)N=N2
Biological Activity: Xanthine oxidase-IN-5 is an effective and orally active xanthine oxidase (XO) inhibitor with IC50 value of 0.70 μM. Xanthine oxidase-IN-5 displays favorable agent-like properties with ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 shows potent hypouricemic effects in hyperuricemic rat model[1].
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Xanthine oxidase-IN-5 | Xanthine oxidase-IN-5 is an effective and orally active xanthine oxidase (XO) inhibitor with IC50 value of 0.70 μM. Xanthine oxidase-IN-5 displays favorable agent-like properties with ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 shows potent hypouricemic effects in hyperuricemic rat model. | |||||||||||||||||||||
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Keywords
