2280834-99-1
Chemical Structure
CYP4A11/CYP4F2-IN-2
- CAS No.: 2280834-99-1
- Formula:C19H27N3O4
- Molecular Weight:361.44
InChIKey: IMRNTQAZUTUQAV-UHFFFAOYSA-N
SMILES: CC(C)(C(O)=O)OCCCCCCCOC1=CC=C(C2=CC=NN2)N=C1
Biological Activity: CYP4A11/CYP4F2-IN-2 (compound 15) is an orally available inhibitor of CYP4A11/4F2 with IC50s of 120 nM and 220 nM, respectively. CYP4A11/CYP4F2-IN-2 inhibits 20-HETE production in rat kidney and has potential inhibitory effects on diabetic nephropathy and autosomal dominant polycystic kidney disease[1].
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CYP4A11/CYP4F2-IN-2 | CYP4A11/CYP4F2-IN-2 (compound 15) is an orally available inhibitor of CYP4A11/4F2 with IC50s of 120 nM and 220 nM, respectively. CYP4A11/CYP4F2-IN-2 inhibits 20-HETE production in rat kidney and has potential inhibitory effects on diabetic nephropathy and autosomal dominant polycystic kidney disease. | |||||||||||||||||||||
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Keywords