2281766-67-2
2281766-67-2
Chemical Structure
KDM5A-IN-2
- CAS No.: 2281766-67-2
- Formula:C28H34N4O4S
- Molecular Weight:522.66
IUPAC Name: (E)-2-((3-(4-(dimethylamino)but-2-enamido)phenyl)(2-(piperidin-1-yl)ethoxy)methyl)thieno[3,2-b]pyridine-7-carboxylic acid
InChIKey: KIIDGZQVWULCMZ-JXMROGBWSA-N
SMILES: O=C(C1=C2C(C=C(C(C3=CC=CC(NC(/C=C/CN(C)C)=O)=C3)OCCN4CCCCC4)S2)=NC=C1)O
Biological Activity: KDM5A-IN-2 is a KDM5A inhibitor. The human IC50 values of KDM5A-IN-2 for KDM5A, KDM5B, and KDM4A are 0.11 μM, 0.22 μM, and 5.3 μM, respectively. KDM5A-IN-2 inhibits KDM5B- and KDM4A-mediated histone lysine demethylation[1].
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KDM5A-IN-2 | KDM5A-IN-2 is a KDM5A inhibitor. The human IC50 values of KDM5A-IN-2 for KDM5A, KDM5B, and KDM4A are 0.11 μM, 0.22 μM, and 5.3 μM, respectively. KDM5A-IN-2 inhibits KDM5B- and KDM4A-mediated histone lysine demethylation. | |||||||||||||||||||||
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