23141-25-5
Chemical Structure
Strictosamide
- CAS No.: 23141-25-5
- Formula:C26H30N2O8
- Molecular Weight:498.53
IUPAC Name: (1R,2S,13bS,14aS)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1-vinyl-1,2,7,8,13,13b,14,14a-octahydro-5H-indolo[2,3-a]pyrano[3,4-g]quinolizin-5-one
InChIKey: LBRPLJCNRZUXLS-IUNANRIWSA-N
SMILES: O=C1N2CCC3=C(NC4=C3C=CC=C4)[C@]2([H])C[C@]5([H])C1=CO[C@@H](O[C@H]6[C@@H]([C@H]([C@@H]([C@@H](CO)O6)O)O)O)[C@@H]5C=C
Biological Activity: Strictosamide is a compound that can be isolated from Nauclea officinalis. Strictosamide has various activities such as anti-inflammatory, analgesic, anti-Plasmodium, antifungal, and promoting wound healing[1][2][3][4][5].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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Strictosamide | 99.94% | Strictosamide is a compound that can be isolated from Nauclea officinalis. Strictosamide has various activities such as anti-inflammatory, analgesic, anti-Plasmodium, antifungal, and promoting wound healing. | ||||||||||||||||||||
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References
- [1]. Li D, et al. Anti-inflammatory effect of the six compounds isolated from Nauclea officinalis Pierrc ex Pitard, and molecular mechanism of strictosamide via suppressing the NF-κB and MAPK signaling pathway in LPS-induced RAW 264.7 macrophages. J Ethnopharmacol. 2017 Jan 20;196:66-74. [Content Brief]
- [2]. Candeias MF, et al. Effects of strictosamide on mouse brain and kidney Na+, K+-ATPase and Mg2+-ATPase activities. J Ethnopharmacol. 2009 Jan 12;121(1):117-22. [Content Brief]
- [3]. Na Li, et al. In vivo anti-inflammatory and analgesic activities of strictosamide from Nauclea officinalis. Pharm Biol. 2014 Nov;52(11):1445-50. [Content Brief]
- [4]. Ming GX, et al. Strictosamide promotes wound healing through activation of the PI3K/AKT pathway. Heliyon. 2024 Apr 23;10(9):e30169. [Content Brief]
