2315450-35-0

Kv7.2/Kv7.3 agonist 1 Chemical Structure
2315450-35-0

Chemical Structure

Kv7.2/Kv7.3 agonist 1

  • CAS No.: 2315450-35-0
  • Formula:C14H14FN3O2
  • Molecular Weight:275.28

SMILES: CC(NC1=NC(OCC2=CC=C(F)C=C2)=CC=C1N)=O

Biological Activity: Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally active agonist for KV7.2/7.3 channel (KCNQ2/3) with an EC50 of 1.03 μM. Kv7.2/Kv7.3 agonist 1 exhibits analgesic efficacy in mice chronic constriction injury (CCI) model and mice Streptozotocin (HY-13753)-induced diabetic peripheral neuropathic pain (DPNP) model, with ED50 of 12.02 and 9.63 mg/kg[1].

Cat. No. Product Name Purity Description Pricing
HY-168214 		Kv7.2/Kv7.3 agonist 1 Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally active agonist for KV7.2/7.3 channel (KCNQ2/3) with an EC50 of 1.03 μM. Kv7.2/Kv7.3 agonist 1 exhibits analgesic efficacy in mice chronic constriction injury (CCI) model and mice Streptozotocin (HY-13753)-induced diabetic peripheral neuropathic pain (DPNP) model, with ED50 of 12.02 and 9.63 mg/kg.
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