2316765-79-2
2316765-79-2
Chemical Structure
17β-HSD10-IN-2
- CAS No.: 2316765-79-2
- Formula:C15H10ClN3O4S
- Molecular Weight:363.78
InChIKey: MLYXMALTIGQLLF-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C(Cl)=C1)O)NC2=NC3=CC=C(C(O)=O)C=C3S2
Biological Activity: 17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer[1].
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17β-HSD10-IN-2 | 17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer. | |||||||||||||||||||||
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References
Keywords
