2320953-89-5
2320953-89-5
Chemical Structure
GSK591 hydrochloride
Synonym(s): EPZ015866 hydrochloride; GSK3203591 hydrochloride
- CAS No.: 2320953-89-5
- Formula:C22H30Cl2N4O2
- Molecular Weight:453.41
IUPAC Name: (S)-2-(cyclobutylamino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide dihydrochloride
InChIKey: CDKUMVXFXBTOBE-FJSYBICCSA-N
SMILES: O=C(C1=CC(NC2CCC2)=NC=C1)NC[C@H](O)CN3CC4=C(C=CC=C4)CC3.Cl.Cl
Biological Activity: GSK591 (EPZ015866) hydrochloride is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM[1].
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GSK591 hydrochloride | GSK591 (EPZ015866) hydrochloride is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM. | |||||||||||||||||||||
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Keywords
