2328070-52-4

Pomalidomide-amido-PEG3-C2-NH2 Chemical Structure
2328070-52-4

Chemical Structure

Pomalidomide-amido-PEG3-C2-NH2

Synonym(s): Cereblon Ligand-Linker Conjugates 22; E3 ligase Ligand-Linker Conjugates 55

  • CAS No.: 2328070-52-4
  • Formula:C22H28N4O8
  • Molecular Weight:476.48

IUPAC Name: 3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)propanamide

InChIKey: FEXCPYUYLOFYGF-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCOCCOCCOCCN

Biological Activity: Pomalidomide-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].

Cat. No. Product Name Purity Description Pricing
HY-130521
Pomalidomide-amido-PEG3-C2-NH2 99.11% Pomalidomide-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References