2341840-98-8
Chemical Structure
dBRD9 dihydrochloride
- CAS No.: 2341840-98-8
- Formula:C40H47Cl2N7O10
- Molecular Weight:856.75
IUPAC Name: tert-butyl 3-ethoxy-2,2-dimethyl-4-oxobutanoate
InChIKey: CSEVDQHYSARWTE-UHFFFAOYSA-N
SMILES: O=C(NCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN(CC4=C(OC)C=C(C(C5=CC=NC=C65)=CN(C)C6=O)C=C4OC)C.Cl.Cl
Biological Activity: dBRD9 dihydrochloride is a BRD9 PROTAC degrader. dBRD9 dihydrochloride reduces the binding of the ISGF3 complex to ISG promoters, decreases the level of ISG induction downstream of IFNAR signaling, and reduces the chromatin binding of BRD4 at BRD9 co-binding sites. dBRD9 dihydrochloride can be used in research related to acute myeloid leukemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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dBRD9 dihydrochloride | 99.91% | dBRD9 dihydrochloride is a BRD9 PROTAC degrader. dBRD9 dihydrochloride reduces the binding of the ISGF3 complex to ISG promoters, decreases the level of ISG induction downstream of IFNAR signaling, and reduces the chromatin binding of BRD4 at BRD9 co-binding sites. dBRD9 dihydrochloride can be used in research related to acute myeloid leukemia. | ||||||||||||||||||||
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Keywords
