2342576-75-2
2342576-75-2
Chemical Structure
ASM-IN-3
- CAS No.: 2342576-75-2
- Formula:C17H13ClN2O4
- Molecular Weight:344.75
SMILES: O=C(C1=CC(OCC2=CC=C(C3=CC=C(Cl)C=C3)C=C2)=NO1)NO
Biological Activity: ASM-IN-3 (Compound 21b) is a selective and BBB-penetrating acid sphingomyelinase (ASM) inhibitor (IC50: 3.37 μM for pure human ASM). ASM-IN-3 improves depression-like behaviors by inhibiting ASM activity and increasing neurogenesis in hippocampus in Reserpine (HY-N0480)-induced depressed rats[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ASM-IN-3 | ASM-IN-3 (Compound 21b) is a selective and BBB-penetrating acid sphingomyelinase (ASM) inhibitor (IC50: 3.37 μM for pure human ASM). ASM-IN-3 improves depression-like behaviors by inhibiting ASM activity and increasing neurogenesis in hippocampus in Reserpine (HY-N0480)-induced depressed rats. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
