2358677-26-4
Chemical Structure
PA-SiR-Halo
- CAS No.: 2358677-26-4
- Formula:C33H50ClN3O3Si
- Molecular Weight:600.31
InChIKey: TZDMPQGLQRMOHO-UHFFFAOYSA-N
SMILES: O=C(CC/C=C1C2=CC=C(N(C)C)C=C2[Si](C)(C)C3=CC(N(C)C)=CC=C\13)NCCOCCOCCCCCCCl
Biological Activity: PA-SiR-Halo is a photoactivatable fluorophore targeting HaloTag. When bound to HaloTag, PA-SiR-Halo stabilizes its fluorescent form under physiological pH. After conjugation and photoactivation, it exhibits enhanced resistance to nucleophiles, and enables live-cell confocal imaging, fixed-cell single-molecule localization microscopy imaging, live-cell single-particle tracking, as well as live-cell single-molecule localization microscopy imaging of dynamic mitochondrial structures without the need for washing[1][2].
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PA-SiR-Halo | PA-SiR-Halo is a photoactivatable fluorophore targeting HaloTag. When bound to HaloTag, PA-SiR-Halo stabilizes its fluorescent form under physiological pH. After conjugation and photoactivation, it exhibits enhanced resistance to nucleophiles, and enables live-cell confocal imaging, fixed-cell single-molecule localization microscopy imaging, live-cell single-particle tracking, as well as live-cell single-molecule localization microscopy imaging of dynamic mitochondrial structures without the need for washing. | |||||||||||||||||||||
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