2363751-90-8
Chemical Structure
Rhodamine-N3 chloride
- CAS No.: 2363751-90-8
- Formula:C44H59ClN8O7
- Molecular Weight:847.44
IUPAC Name: 9-(2-(4-(1-azido-13-oxo-3,6,9-trioxa-12-azahexadecan-16-oyl)piperazine-1-carbonyl)phenyl)-3,6-bis(diethylamino)xanthylium chloride
InChIKey: JNDTZEVRHDBMAN-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCOCCOCCOCCNC(CCC(N1CCN(CC1)C(C2=C(C3=C4C=CC(N(CC)CC)=CC4=[O+]C5=C3C=CC(N(CC)CC)=C5)C=CC=C2)=O)=O)=O.[Cl-]
Biological Activity: Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye that can be used to label biomolecules containing alkyne groups[1][2]. Rhodamine-N3 chloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 544/576 nm).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Rhodamine-N3 chloride | 99.85% | Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye that can be used to label biomolecules containing alkyne groups. Rhodamine-N3 chloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 544/576 nm). | ||||||||||||||||||||
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References
- [1]. Shijiao Cai, et al. Glycyrrhizic Acid-Induced Differentiation Repressed Stemness in Hepatocellular Carcinoma by Targeting c-Jun N-Terminal Kinase 1. Front Oncol. 2020 Jan 9;9:1431. [Content Brief]
- [2]. Bryan R Lanning, et al. A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors. Nat Chem Biol. 2014 Sep;10(9):760-767. [Content Brief]
