2364479-10-5
2364479-10-5
Chemical Structure
Antibacterial agent 236
- CAS No.: 2364479-10-5
- Formula:C26H27N5O2S
- Molecular Weight:473.59
InChIKey: JUHNMCHIPCQWBR-UHFFFAOYSA-N
SMILES: O=C1NC2=CC(CNC3CCN(CC3)CCN(C4=C(C=C5)C=CC(C#N)=C4)C5=O)=CC=C2SC1
Biological Activity: Antibacterial agent 236 (Compound 4l) is an orally active inhibitor for DNA gyrase and topoisomerase IV (IC50 is 3.2 and 300 nM in Staphylococcus aureus), and exhibits board-spectrum antibacterial activity. Antibacterial agent 236 exhibits good pharmacokinetic properties in mice[1].
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Antibacterial agent 236 | Antibacterial agent 236 (Compound 4l) is an orally active inhibitor for DNA gyrase and topoisomerase IV (IC50 is 3.2 and 300 nM in Staphylococcus aureus), and exhibits board-spectrum antibacterial activity. Antibacterial agent 236 exhibits good pharmacokinetic properties in mice. | |||||||||||||||||||||
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References
Keywords
