23665-96-5
23665-96-5
Chemical Structure
Neogrifolin
- CAS No.: 23665-96-5
- Formula:C22H32O2
- Molecular Weight:328.49
IUPAC Name: 5-methyl-4-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)benzene-1,3-diol
InChIKey: JWDIUXFSIWOGDP-VZRGJMDUSA-N
SMILES: OC1=CC(C)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)C(O)=C1
Biological Activity: Neogrifolin is an inhibitor of KRAS. Neogrifolin suppress KRAS expression in human colon cancer cells. Neogrifolin has anti-cell viability activity against HeLa, SW480 and HT29 cells wih IC50s of 24.3, 34.6, and 30.1 μM, respectively[1].
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Neogrifolin | Neogrifolin is an inhibitor of KRAS. Neogrifolin suppress KRAS expression in human colon cancer cells. Neogrifolin has anti-cell viability activity against HeLa, SW480 and HT29 cells wih IC50s of 24.3, 34.6, and 30.1 μM, respectively. | |||||||||||||||||||||
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