23680-84-4
Chemical Structure
ACDQ
Synonym(s): 4-Amino-2-chloro-6,7-dimethoxyquinazoline
- CAS No.: 23680-84-4
- Formula:C10H10ClN3O2
- Molecular Weight:239.66
IUPAC Name: 2-chloro-6,7-dimethoxyquinazolin-4-amine
InChIKey: HWIIAAVGRHKSOJ-UHFFFAOYSA-N
SMILES: COC1=CC2=NC(Cl)=NC(N)=C2C=C1OC
Biological Activity: ACDQ (4-Amino-2-chloro-6,7-dimethoxyquinazoline) is a pharmaceutical intermediate that can be used for the synthesis of quinazoline-based antibacterial agents. Molecular docking results of ACDQ indicate that it possesses potential acetylcholinesterase inhibitory activity, and it can be applied to Alzheimer's disease-related research[1][2].
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ACDQ | 98.0% | ACDQ (4-Amino-2-chloro-6,7-dimethoxyquinazoline) is a pharmaceutical intermediate that can be used for the synthesis of quinazoline-based antibacterial agents. Molecular docking results of ACDQ indicate that it possesses potential acetylcholinesterase inhibitory activity, and it can be applied to Alzheimer's disease-related research. | ||||||||||||||||||||
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- [1]. Kung PP, et al. Structure-activity relationships of novel 2-substituted quinazoline antibacterial agents. Journal of medicinal chemistry. 1999 Nov 04;42(22):4705-13. [Content Brief]
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[2]. Asokan K, et al. Combined Experimental and Computational Investigations of 4‑Amino‑2‑Chloro‑6,7‑Dimethoxyquinazoline as Potential Anti‑Alzheimer Agent. International Journal of Quantum Chemistry, 2024, 124(24): e27527.
Keywords
