2374894-21-8
2374894-21-8
Chemical Structure
CB2 receptor agonist 9
- CAS No.: 2374894-21-8
- Formula:C16H23N3O2S
- Molecular Weight:321.44
InChIKey: SFVBCXZJTQTCLI-UHFFFAOYSA-N
SMILES: CCCCN1N=C(C=C1C2=CC=CS2)C(NC(C)(CO)C)=O
Biological Activity: CB2 receptor agonist 9 (Compound 33) is an orally active agonist for cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. CB2 receptor agonist 9 inhibits the expression of TNF-α, IL-1β and IL-6, exhibits anti-inflammatory efficacy in DDS (HY-116282)-induced mouse acute colitis model[1].
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CB2 receptor agonist 9 | CB2 receptor agonist 9 (Compound 33) is an orally active agonist for cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. CB2 receptor agonist 9 inhibits the expression of TNF-α, IL-1β and IL-6, exhibits anti-inflammatory efficacy in DDS (HY-116282)-induced mouse acute colitis model. | |||||||||||||||||||||
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