2375070-79-2
Chemical Structure
MS48107
- CAS No.: 2375070-79-2
- Formula:C23H20FN5O2
- Molecular Weight:417.44
IUPAC Name: (2-(4-amino-6-((4-phenoxybenzyl)amino)-1,3,5-triazin-2-yl)-3-fluorophenyl)methanol
InChIKey: KKHDNAZPEMYUNO-UHFFFAOYSA-N
SMILES: OCC1=CC=CC(F)=C1C2=NC(N)=NC(NCC3=CC=C(OC4=CC=CC=C4)C=C3)=N2
Biological Activity: MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). MS48107 is selective for GPR68 over the closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. MS48107 can readily cross the blood-brain barrier (BBB) in mice[1].
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MS48107 | 99.90% | MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). MS48107 is selective for GPR68 over the closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. MS48107 can readily cross the blood-brain barrier (BBB) in mice. | ||||||||||||||||||||
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Keywords