2375564-62-6
Chemical Structure
VHL Ligand-Linker Conjugates 15
Synonym(s): E3 Ligase Ligand-Linker Conjugates 56
- CAS No.: 2375564-62-6
- Formula:C37H45FN4O8S
- Molecular Weight:724.84
IUPAC Name: (2S,4R)-N-(2-(2-(4-(1,3-dioxolan-2-yl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide
InChIKey: WBMXUVVXKXJJQS-PNBNRWGDSA-N
SMILES: O=C(NCC1=CC=C(C=C1OCCOC2=CC=C(C=C2)C3OCCO3)C4=C(N=CS4)C)[C@H]5N(C[C@@H](C5)O)C([C@H](C(C)(C)C)NC(C6(CC6)F)=O)=O
Biological Activity: VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs[1].
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VHL Ligand-Linker Conjugates 15 | VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs. | |||||||||||||||||||||
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