2376333-77-4
2376333-77-4
Chemical Structure
Dopamine D3 receptor ligand-4
- CAS No.: 2376333-77-4
- Formula:C26H28N4OS
- Molecular Weight:444.59
IUPAC Name: N-(4-(4-(3-cyanophenyl)piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamide
InChIKey: AWLLDUFWUOASGN-UHFFFAOYSA-N
SMILES: O=C(NCCCCN1CCN(C2=CC=CC(C#N)=C2)CC1)C3=CC=C(C4=CSC=C4)C=C3
Biological Activity: Dopamine D3 receptor ligand-4 (compound 6) is a potent and selective dopamine D3 receptor ligand, with a Ki of 0.5 nM. Dopamine D3 receptor ligand-4 shows high level of selectivity for D3 over D2 (Ki=7.43 nM)[1].
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Dopamine D3 receptor ligand-4 | Dopamine D3 receptor ligand-4 (compound 6) is a potent and selective dopamine D3 receptor ligand, with a Ki of 0.5 nM. Dopamine D3 receptor ligand-4 shows high level of selectivity for D3 over D2 (Ki=7.43 nM). | |||||||||||||||||||||
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References
Keywords
