2377167-56-9

HEI3090 Chemical Structure
2377167-56-9

Chemical Structure

HEI3090

  • CAS No.: 2377167-56-9
  • Formula:C18H15Cl3N4O3
  • Molecular Weight:441.70

InChIKey: XFDLAUDFTNZPNJ-AWEZNQCLSA-N

SMILES: ClC1=NC=C(C=C1)NC(N2[C@@H](CCC2=O)C(NCC3=C(C=C(C=C3)Cl)Cl)=O)=O

Biological Activity: HEI3090 is a P2X7R activator. HEI3090 stimulates dendritic cells expressing P2X7R to produce IL-18, which subsequently promotes Natural Killer cells and CD4 T cells within tumors to produce IFN-γ, leading to a sustained antitumor response. HEI3090 can be used to enhance the efficacy of αPD-1 therapy in non-small cell lung cancer (NSCLC)[1].

Cat. No. Product Name Purity Description Pricing
HY-164426 		HEI3090 99.00% HEI3090 is a P2X7R activator. HEI3090 stimulates dendritic cells expressing P2X7R to produce IL-18, which subsequently promotes Natural Killer cells and CD4 T cells within tumors to produce IFN-γ, leading to a sustained antitumor response. HEI3090 can be used to enhance the efficacy of αPD-1 therapy in non-small cell lung cancer (NSCLC).
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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