2377916-66-8
2377916-66-8
Chemical Structure
PD-1/PD-L1-IN-NP19
- CAS. Nr.: 2377916-66-8
- Formula:C33H31ClN2O4
- Molecular Weight:555.06
IUPAC Name: 2-((5-chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)amino)-2-methylpropanoic acid
InChIKey: YZPKZNFXWGTUGO-UHFFFAOYSA-N
SMILES: CC(C)(NCC1=CC(Cl)=C(OCC2=C(C)C(C3=CC=CC=C3)=CC=C2)C=C1OCC4=CC=CC(C#N)=C4)C(O)=O
Biological Activity: PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12.5 nM for human PD-1/PD-L1 interaction. PD-1/PD-L1-IN-NP19 could activate the immune microenvironment in tumor, which may contribute to its antitumor effects[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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PD-1/PD-L1-IN-NP19 | 98.25% | PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12.5 nM for human PD-1/PD-L1 interaction. PD-1/PD-L1-IN-NP19 could activate the immune microenvironment in tumor, which may contribute to its antitumor effects. | ||||||||||||||||||||
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