2380-63-4
2380-63-4
Chemical Structure
Pyrazoloadenine
- CAS No.: 2380-63-4
- Formula:C5H5N5
- Molecular Weight:135.13
IUPAC Name: 1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChIKey: LHCPRYRLDOSKHK-UHFFFAOYSA-N
SMILES: NC1=C2C(NN=C2)=NC=N1
Biological Activity: Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity[1][2].
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Pyrazoloadenine | 99.98% | Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity. | ||||||||||||||||||||
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Pyrazoloadenine (Standard) | ≥98% | Pyrazoloadenine (Standard) is the analytical standard of Pyrazoloadenine. This product is intended for research and analytical applications. Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity. | ||||||||||||||||||||
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References
- [1]. Saha D, et al. Pyrazoloadenine Inhibitors of the RET Lung Cancer Oncoprotein Discovered by a Fragment Optimization Approach. ChemMedChem. 2021 May 18;16(10):1605-1608. [Content Brief]
- [2]. SKIPPER HE, et al. Inhibition of experimental neoplasms by 4-aminopyrazolo (3, 4-d) pyrimidine. Proc Soc Exp Biol Med. 1955 Aug;89(4):594-6. [Content Brief]
