2380-94-1
Chemical Structure
4-Hydroxyindole
- CAS No.: 2380-94-1
- Formula:C8H7NO
- Molecular Weight:133.15
IUPAC Name: 1H-indol-4-ol
InChIKey: NLMQHXUGJIAKTH-UHFFFAOYSA-N
SMILES: OC1=CC=CC2=C1C=CN2
Biological Activity: 4-Hydroxyindole is a type of hydroxyindole in which the 1H-indole at position 4 is substituted by a hydroxyl group. 4-Hydroxyindole serves as an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers. 4-Hydroxyindole inhibits amyloid fibrillization and induces liver function impairment, thyroid abnormalities, and blood glucose fluctuations in mice. 4-Hydroxyindole holds potential for research in neurodegenerative diseases and metabolic disorders[1][2][3].
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4-Hydroxyindole | 98.06% | 4-Hydroxyindole is a type of hydroxyindole in which the 1H-indole at position 4 is substituted by a hydroxyl group. 4-Hydroxyindole serves as an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers. 4-Hydroxyindole inhibits amyloid fibrillization and induces liver function impairment, thyroid abnormalities, and blood glucose fluctuations in mice. 4-Hydroxyindole holds potential for research in neurodegenerative diseases and metabolic disorders. | ||||||||||||||||||||
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4-Hydroxyindole (Standard) | ≥98% | 4-Hydroxyindole (Standard) is the analytical standard of 4-Hydroxyindole. This product is intended for research and analytical applications. 4-Hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. 4-Hydroxyindole is an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers. | ||||||||||||||||||||
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- [1]. Nenad Manevski, et al. Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases. Drug Metab Dispos. 2010 Mar;38(3):386-95. [Content Brief]
- [2]. Cohen T, et al. Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives. Biochemistry. 2006 Apr 18;45(15):4727-35. [Content Brief]
- [3]. Goyal R N, et al. Electrochemical oxidation of 4-hydroxyindole and effects of its oxidation products on blood parameters of albino mice[J]. Bioorganic Chemistry, 1999, 27(3): 239-252.
