2385-77-5
Chemical Structure
(R)-(+)-Citronellal
Synonym(s): (+)-Citronellal
- CAS No.: 2385-77-5
- Formula:C10H18O
- Molecular Weight:154.25
IUPAC Name: (R)-3,7-dimethyloct-6-enal
InChIKey: NEHNMFOYXAPHSD-SNVBAGLBSA-N
SMILES: C/C(C)=C\CC[C@@H](C)CC=O
Biological Activity: (R)-(+)-Citronellal ((+)-Citronellal) is a monoterpenoid compound and is one of the main components of essential oils from plants such as lemon grass. (R)-(+)-Citronellal has antibacterial, antifungal, and insecticidal activities. (R)-(+)-Citronellal alleviates the bitterness of caffeine by antagonizing the bitter taste receptors Tas2r43 (IC50 = 84 μM) and Tas2R46. (R)-(+)-Citronellal generates analgesic activity by activating the opioid receptor (broad-spectrum opioid receptor) pathway, and its effect is particularly significant for inflammatory pain[1][2][3][4].
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(R)-(+)-Citronellal | 98.72% | (R)-(+)-Citronellal ((+)-Citronellal) is a monoterpenoid compound and is one of the main components of essential oils from plants such as lemon grass. (R)-(+)-Citronellal has antibacterial, antifungal, and insecticidal activities. (R)-(+)-Citronellal alleviates the bitterness of caffeine by antagonizing the bitter taste receptors Tas2r43 (IC50 = 84 μM) and Tas2R46. (R)-(+)-Citronellal generates analgesic activity by activating the opioid receptor (broad-spectrum opioid receptor) pathway, and its effect is particularly significant for inflammatory pain. | ||||||||||||||||||||
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- [1]. Gouveia RG, et al. Antifungal effect of (R) and (S)-citronellal enantiomers and their predictive mechanism of action on Candida albicans from voriconazole-resistant onychomycoses. Braz J Biol. 2023 May 22;83:e271530. [Content Brief]
- [2]. Wu P, et al. Chemical Composition, Antimicrobial and Insecticidal Activities of Essential Oils of Discarded Perfume Lemon and Leaves (Citrus Limon (L.) Burm. F.) as Possible Sources of Functional Botanical Agents. Front Chem. 2021 May 24;9:679116. [Content Brief]
- [3]. Suess B, et al. The Odorant ( R)-Citronellal Attenuates Caffeine Bitterness by Inhibiting the Bitter Receptors TAS2R43 and TAS2R46. J Agric Food Chem. 2018 Mar 14;66(10):2301-2311. [Content Brief]
- [4]. Costa AOC, et al. Evaluation of the antinociceptive effect generated by citronellal monoterpene isomers. Braz J Biol. 2023 May 29;83:e271781. [Content Brief]
Keywords
