2408406-89-1

P-gp inhibitor 2 Chemical Structure
2408406-89-1

Chemical Structure

P-gp inhibitor 2

  • CAS No.: 2408406-89-1
  • Formula:C29H26N2O6
  • Molecular Weight:498.53

IUPAC Name: (3R,11S,11aS)-2-acetyl-3-benzoyl-11-(7-methoxybenzo[d][1,3]dioxol-5-yl)-1,2,3,4,11,11a-hexahydro-6H-pyrazino[1,2-b]isoquinolin-6-one

InChIKey: IDANOMWCBLGPHR-PLXFJCCSSA-N

SMILES: O=C1N2[C@@](CN([C@H](C2)C(C3=CC=CC=C3)=O)C(C)=O)([H])[C@](C4=CC(OC)=C(OCO5)C5=C4)([H])C6=CC=CC=C61

Biological Activity: P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300)[1].

Cat. No. Product Name Purity Description Pricing
HY-N144114
P-gp inhibitor 2 P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300).
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References