2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. P-gp inhibitor 2

P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300).

For research use only. We do not sell to patients.

P-gp inhibitor 2 Chemical Structure

P-gp inhibitor 2 Chemical Structure

CAS No. : 2408406-89-1

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P-gp inhibitor 2 Related Antibodies

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Description

P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300)[1].

In Vitro

P-gp inhibitor 2 (compound 2) exhibits no cytotoxicity (IC50>30 µM) toward human carcinoma (SW600) cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

P-gp inhibitor 2 Related Antibodies
Molecular Weight

498.53

Formula

C29H26N2O6
CAS No.
SMILES

O=C1N2[C@@](CN([C@H](C2)C(C3=CC=CC=C3)=O)C(C)=O)([H])[C@](C4=CC(OC)=C(OCO5)C5=C4)([H])C6=CC=CC=C61
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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P-gp inhibitor 2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

P-gp inhibitor 22408406-89-1P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243pharmacophoreMarine-Derived fungalSW600 Ad300 cellschrysosporazinedoxorubicincytotoxicityInhibitorinhibitorinhibit

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P-gp inhibitor 2
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HY-N144114
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