2409952-04-9
2409952-04-9
Chemical Structure
Antitumor agent-59
- CAS No.: 2409952-04-9
- Formula:C43H36F2N6O6
- Molecular Weight:770.78
IUPAC Name: bis(3-fluoro-14-methyl-5-oxo-5,7,8,13,13b,14-hexahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-10-yl) glutarate
InChIKey: SEGHRBDHWNUBHD-UHFFFAOYSA-N
SMILES: CN1C2=C(C(N3CCC4=C(C13)NC5=CC=C(C=C54)OC(CCCC(OC6=CC=C7NC8=C(C7=C6)CCN9C(C%10=C(N(C89)C)C=CC(F)=C%10)=O)=O)=O)=O)C=C(C=C2)F
Biological Activity: Antitumor agent-59 (Compound 13b) is a potent antitumor agent. Antitumor agent-59 effectively inhibits the proliferation and migration of HCT116 cells. Antitumor agent-59 induces HCT116 cell apoptosis and arrests the cell cycle at the G2/M phase[1].
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Antitumor agent-59 | Antitumor agent-59 (Compound 13b) is a potent antitumor agent. Antitumor agent-59 effectively inhibits the proliferation and migration of HCT116 cells. Antitumor agent-59 induces HCT116 cell apoptosis and arrests the cell cycle at the G2/M phase. | |||||||||||||||||||||
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