2411580-63-5
2411580-63-5
Chemical Structure
Peresolimab
Synonym(s): LY-3462817
- CAS No.: 2411580-63-5
- Formula:N/A
- Molecular Weight:(145.16 kDa)
IUPAC Name: 2-(3,4-dihydroxybenzyl)-2-hydrazinylpropanoic-3-13C-3,3,3-d3 acid
SMILES: [Peresolimab]
Biological Activity: Peresolimab is a humanized IgG1-κ antibody targeting to PD-1. Peresolimab potentially stimulates physiological immune inhibitory pathways to restore immune homeostasis. Peresolimab can be used in research of rheumatoid arthritis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Peresolimab | 99.62% | Peresolimab is a humanized IgG1-κ antibody targeting to PD-1. Peresolimab potentially stimulates physiological immune inhibitory pathways to restore immune homeostasis. Peresolimab can be used in research of rheumatoid arthritis. | ||||||||||||||||||||
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References
- [1]. Tuttle J, et al. Phase 2 Trial of Peresolimab for Adults with Rheumatoid Arthritis. Reply. N Engl J Med. 2023 Jul 27;389(4):378-379. [Content Brief]
- [2]. Leane CM, et al., PD-1 regulation of pathogenic IL-17-secreting γδ T cells in experimental autoimmune encephalomyelitis. Eur J Immunol. 2024 Oct;54(10):e2451212. [Content Brief]
