2413962-65-7
2413962-65-7
Chemical Structure
Calpain Inhibitor-2
- CAS No.: 2413962-65-7
- Formula:C26H33N3O5S
- Molecular Weight:499.62
IUPAC Name: (S)-5-methyl-3-((S)-3-methyl-2-((4-((E)-styryl)phenyl)sulfonamido)butanamido)-2-oxohexanamide
InChIKey: WNWIOVLJZSTYAN-TZFKZXSBSA-N
SMILES: CC(C[C@@H](C(C(N)=O)=O)NC([C@H](C(C)C)NS(=O)(C1=CC=C(C=C1)/C=C/C2=CC=CC=C2)=O)=O)C
Biological Activity: Calpain Inhibitor-2 (compound 5) is a peptide inhibitor of μ-calpain (Ki=9 nM). Calpain Inhibitor-2 exhibits antiproliferative activity against melanoma cell lines (A-375 and B-16F1) and PC-3 prostate cancer cells in vitro[1].
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Calpain Inhibitor-2 | Calpain Inhibitor-2 (compound 5) is a peptide inhibitor of μ-calpain (Ki=9 nM). Calpain Inhibitor-2 exhibits antiproliferative activity against melanoma cell lines (A-375 and B-16F1) and PC-3 prostate cancer cells in vitro. | |||||||||||||||||||||
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