2415085-45-7
2415085-45-7
Chemical Structure
PDE4-IN-8
- CAS No.: 2415085-45-7
- Formula:C18H22BNO4
- Molecular Weight:327.18
IUPAC Name: (S)-4-(5-(4-methoxy-3-propoxyphenyl)pyridin-3-yl)-1,2-oxaborolan-2-ol
InChIKey: KXVKOYCGACSUPP-MRXNPFEDSA-N
SMILES: CCCOC1=C(OC)C=CC(C2=CN=CC([C@]3([H])CB(OC3)O)=C2)=C1
Biological Activity: PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM)[1].
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PDE4-IN-8 | PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM). | |||||||||||||||||||||
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References
Keywords
