PDE4-IN-8
PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM).
For research use only. We do not sell to patients.
- CAS No.: 2415085-45-7
- Formula: C18H22BNO4
- Molecular Weight:327.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PDE4B2 0.93 nM (IC50) |
IL4 36.33 nM (IC50) |
IL-13 4.04 nM (IC50) |
Chemical Information
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CAS No. 2415085-45-7
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Molecular Weight 327.18
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Formula C18H22BNO4
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SMILES
CCCOC1=C(OC)C=CC(C2=CN=CC([C@]3([H])CB(OC3)O)=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)