2415330-05-9
2415330-05-9
Chemical Structure
Zorevunersen sodium
Synonym(s): STK-001 sodium
- CAS No.: 2415330-05-9
- Formula:C234H317N71Na17O124P17S17
- Molecular Weight:7197.2 (free acid)
SMILES: [Zorevunersen (sodium)]
Biological Activity: Zorevunersen sodium is an antisense oligonucleotide targeting the Scn1a gene based on TANGO technology. Zorevunersen sodium increases Scn1a mRNA transcripts and elevates the expression level of NaV1.1 protein. Zorevunersen sodium restores the excitability of PV interneurons, thereby reducing seizures and prolonging survival in mice. Zorevunersen sodium can be used for research on Dravet syndrome[1].
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Zorevunersen sodium | 99.27% | Zorevunersen sodium is an antisense oligonucleotide targeting the Scn1a gene based on TANGO technology. Zorevunersen sodium increases Scn1a mRNA transcripts and elevates the expression level of NaV1.1 protein. Zorevunersen sodium restores the excitability of PV interneurons, thereby reducing seizures and prolonging survival in mice. Zorevunersen sodium can be used for research on Dravet syndrome. | ||||||||||||||||||||
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References
Keywords
