2417988-00-0
Chemical Structure
JB062
- CAS No.: 2417988-00-0
- Formula:C19H17NO4
- Molecular Weight:323.34
IUPAC Name: (E)-4-hydroxy-3-(1-((4-methoxybenzyl)imino)ethyl)-2H-chromen-2-one
InChIKey: VNZQIXKYYHQDBZ-UDWIEESQSA-N
SMILES: OC(C1=CC=CC=C1O2)=C(/C(C)=N/CC3=CC=C(OC)C=C3)C2=O
Biological Activity: JB062 is a nonmuscle myosin inhibitor with IC50 values of 1.6, 5.4, and >100 μM for Skeletal muscle myosin, Cardiac muscle myosin, and Smooth muscle myosin II, respectively. JB062 has cytotoxic to human cancer cells but not normal cells. JB062 can be used in research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].
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JB062 | JB062 is a nonmuscle myosin inhibitor with IC50 values of 1.6, 5.4, and >100 μM for Skeletal muscle myosin, Cardiac muscle myosin, and Smooth muscle myosin II, respectively. JB062 has cytotoxic to human cancer cells but not normal cells. JB062 can be used in research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy. | |||||||||||||||||||||
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Keywords
