24346-00-7
Chemical Structure
S-(5'-Adenosyl)-L-methionine chloride
- CAS No.: 24346-00-7
- Formula:C15H23ClN6O5S
- Molecular Weight:434.90
IUPAC Name: 1,2,4-trimethylcyclohexane
InChIKey: DYFPQIYEZQULMZ-XKGORWRGSA-N
SMILES: O[C@@H]1[C@H](O)[C@@H](C[S+](C)CC[C@H](N)C([O-])=O)O[C@H]1N2C=NC3=C(N=CN=C32)N.Cl
Biological Activity: S-(5'-Adenosyl)-L-methionine chloride is the endogenous methyl donor in the methionine cycle and numerous methylation reactions, including protein methylation. S-(5'-Adenosyl)-L-methionine chloride can activate cardiac ryanodine receptor RyR2 in a concentration-dependent manner, enhancing the affinity of RyR2 for ryanodine. The Kd of S-(5'-Adenosyl)-L-methionine chloride with MetJ in Escherichia coli is 0.18 mM. S-(5'-Adenosyl)-L-methionine chloride can cause changes in the methylation index of Cisplatin (HY-17394)-sensitive and Cisplatin-resistant ovarian cancer cells. S-(5'-Adenosyl)-L-methionine chloride can be used for methylation-related research[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
S-(5'-Adenosyl)-L-methionine chloride | S-(5'-Adenosyl)-L-methionine chloride is the endogenous methyl donor in the methionine cycle and numerous methylation reactions, including protein methylation. S-(5'-Adenosyl)-L-methionine chloride can activate cardiac ryanodine receptor RyR2 in a concentration-dependent manner, enhancing the affinity of RyR2 for ryanodine. The Kd of S-(5'-Adenosyl)-L-methionine chloride with MetJ in Escherichia coli is 0.18 mM. S-(5'-Adenosyl)-L-methionine chloride can cause changes in the methylation index of Cisplatin (HY-17394)-sensitive and Cisplatin-resistant ovarian cancer cells. S-(5'-Adenosyl)-L-methionine chloride can be used for methylation-related research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
