2435562-99-3
Chemical Structure
FLT3-IN-15
- CAS No.: 2435562-99-3
- Formula:C22H23ClFN5O2
- Molecular Weight:443.90
IUPAC Name: (2Z,3E)-5'-fluoro-3-((2-(piperazin-1-yl)ethoxy)imino)-[2,3'-biindolinylidene]-2'-one hydrochloride
InChIKey: YRBWCJJMWLQUOQ-WCFRLSLOSA-N
SMILES: O=C1NC2=C(/C1=C3NC4=CC=CC=C4C/3=N\OCCN5CCNCC5)C=C(C=C2)F.Cl
Biological Activity: FLT3-IN-15 is a highly potent and orally active FLT3 inhibitor with IC50s of 0.87 nM and 0.32 nM for FLT3 and FLT3/D835Y, respectively. FLT3-IN-15 can be used for researching acute myeloid leukemia[1].
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FLT3-IN-15 | FLT3-IN-15 is a highly potent and orally active FLT3 inhibitor with IC50s of 0.87 nM and 0.32 nM for FLT3 and FLT3/D835Y, respectively. FLT3-IN-15 can be used for researching acute myeloid leukemia. | |||||||||||||||||||||
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Keywords