2435572-48-6
2435572-48-6
Chemical Structure
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2
Synonym(s): Cereblon Ligand-Linker Conjugates 12; E3 Ligase Ligand-Linker Conjugates 23
- CAS No.: 2435572-48-6
- Formula:C25H34N4O9
- Molecular Weight:534.56
IUPAC Name: N-(2-(3-(3-(2-aminoethoxy)propoxy)propoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
InChIKey: YLZGZHLXIFMVEP-UHFFFAOYSA-N
SMILES: O=C(NCCOCCCOCCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Biological Activity: Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
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Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 | Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | |||||||||||||||||||||
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References
