2458163-92-1
2458163-92-1
Chemical Structure
PI3K-IN-33
- CAS No.: 2458163-92-1
- Formula:C23H21BrN6O2
- Molecular Weight:493.36
IUPAC Name: (E)-2-(2-(3-bromobenzylidene)hydrazinyl)-4-(4-methoxyphenyl)-6-morpholinopyrimidine-5-carbonitrile
InChIKey: SLVGYCKNUJAWGA-CVKSISIWSA-N
SMILES: BrC1=CC(/C=N/NC2=NC(N3CCOCC3)=C(C(C4=CC=C(C=C4)OC)=N2)C#N)=CC=C1
Biological Activity: PI3K-IN-33 (Compound 6e) is a highly selective PI3K inhibitor with IC50 values of 11.73, 6.09 and 11.18 μM for PI3K-α、PI3K-β and PI3K-δ , respectively. PI3K-IN-33 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-33 can be used in leukemia research[1].
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PI3K-IN-33 | PI3K-IN-33 (Compound 6e) is a highly selective PI3K inhibitor with IC50 values of 11.73, 6.09 and 11.18 μM for PI3K-α、PI3K-β and PI3K-δ , respectively. PI3K-IN-33 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-33 can be used in leukemia research. | |||||||||||||||||||||
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References
Keywords
