2458163-99-8
2458163-99-8
Chemical Structure
PI3K-IN-35
- CAS No.: 2458163-99-8
- Formula:C25H23N7O2
- Molecular Weight:453.50
IUPAC Name: (E)-2-(2-((1H-indol-3-yl)methylene)hydrazinyl)-4-(4-methoxyphenyl)-6-morpholinopyrimidine-5-carbonitrile
InChIKey: XQXTXAWHZIVHBM-LQKURTRISA-N
SMILES: COC(C=C1)=CC=C1C2=NC(N/N=C/C3=CNC4=C3C=CC=C4)=NC(N5CCOCC5)=C2C#N
Biological Activity: PI3K-IN-35 (Compound 6l) is a highly selective PI3K inhibitor with IC50 values of 13.98, 7.22 and 10.94 μM for PI3K-α、PI3K-β and PI3K-δ, respectively. PI3K-IN-35 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-35 can be used in leukemia research[1].
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PI3K-IN-35 | PI3K-IN-35 (Compound 6l) is a highly selective PI3K inhibitor with IC50 values of 13.98, 7.22 and 10.94 μM for PI3K-α、PI3K-β and PI3K-δ, respectively. PI3K-IN-35 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-35 can be used in leukemia research. | |||||||||||||||||||||
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