2459657-37-3
2459657-37-3
Chemical Structure
Dyrk1A-IN-2
- CAS No.: 2459657-37-3
- Formula:C27H34N6O3
- Molecular Weight:490.60
IUPAC Name: ethyl 6-(2-aminopyridin-4-yl)-4-(((1r,4r)-4-(morpholine-4-carbonyl)cyclohexyl)amino)-1,5-naphthyridine-3-carboxylate
InChIKey: ICDOUZVPXZYHJK-UAPYVXQJSA-N
SMILES: CCOC(C1=C(C2=NC(C3=CC(N)=NC=C3)=CC=C2N=C1)N[C@@H]4CC[C@H](CC4)CN5CCOCC5)=O
Biological Activity: Dyrk1A-IN-2 (Compound 63) is a DYRK1A inhibitor with an EC50 of 37 nM. Dyrk1A-IN-2 exhibits highly potent human β-cell replication-promoting activity and low cytotoxicity[1].
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Dyrk1A-IN-2 | Dyrk1A-IN-2 (Compound 63) is a DYRK1A inhibitor with an EC50 of 37 nM. Dyrk1A-IN-2 exhibits highly potent human β-cell replication-promoting activity and low cytotoxicity. | |||||||||||||||||||||
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