24632-47-1
24632-47-1
Chemical Structure
Nifurpipone
- CAS No.: 24632-47-1
- Formula:C12H17N5O4
- Molecular Weight:295.29
IUPAC Name: (E)-2-(4-methylpiperazin-1-yl)-N'-((5-nitrofuran-2-yl)methylene)acetohydrazide
InChIKey: FHHFNHFFCVLLHX-MDWZMJQESA-N
SMILES: CN1CCN(CC1)CC(N/N=C/C2=CC=C([N+]([O-])=O)O2)=O
Biological Activity: Nifurpipone is an orally active broad-spectrum antimicrobial agent. Nifurpipone acts against Gram-positive and Gram-negative bacteria, and reduces bacterial loads in systemic, intramuscular and urinary tract infections in mouse models. Nifurpipone can be used in studies related to bacterial infections[1][2].
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Nifurpipone | Nifurpipone is an orally active broad-spectrum antimicrobial agent. Nifurpipone acts against Gram-positive and Gram-negative bacteria, and reduces bacterial loads in systemic, intramuscular and urinary tract infections in mouse models. Nifurpipone can be used in studies related to bacterial infections. | |||||||||||||||||||||
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References
- [1]. E. MASSARANI, et al. Antibacterial nitrofuran derivatives. 2. 5-Nitro-2-furaldehyde aminoacethydrazones. Journal of Medicinal Chemistry, 1971, Vol. 14, No.7
- [2]. Massarani E, et al. Nifurpipone, a new nitrofuran with a large antimicrobial spectrum. Experientia. 1971 Oct 15;27(10):1243-4. [Content Brief]
