2468029-34-5
2468029-34-5
Chemical Structure
2-Furoyl-LIGRLO-amide TFA
- CAS No.: 2468029-34-5
- Formula:C38H64F3N11O10
- Molecular Weight:891.98
InChIKey: GGAPZASUUCRPNF-OIQQVIETSA-N
SMILES: NCCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC(C1=CC=CO1)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Biological Activity: 2-Furoyl-LIGRLO-amide TFA is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0[1][2]..
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2-Furoyl-LIGRLO-amide TFA | 2-Furoyl-LIGRLO-amide TFA is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0.. | |||||||||||||||||||||
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References
- [1]. McGuire JJ, et al. 2-furoyl-LIGRLO-amide: a potent and selective proteinase-activated receptor 2 agonist. J Pharmacol Exp Ther. 2004 Jun;309(3):1124-31. [Content Brief]
- [2]. Lohman RJ, et al. An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. FASEB J. 2012 Jul;26(7):2877-87. [Content Brief]
Keywords
