2469044-23-1
2469044-23-1
Chemical Structure
IDH2R140Q-IN-1
- CAS No.: 2469044-23-1
- Formula:C22H20F6N6
- Molecular Weight:482.42
IUPAC Name: 35-(trifluoromethyl)-16-(6-(trifluoromethyl)pyridin-2-yl)-2,10-diaza-1(2,4)-triazina-3(1,3)-benzenacyclodecaphane
InChIKey: UTJJIEVWKZKWEI-UHFFFAOYSA-N
SMILES: FC(C1=CC=CC(C2=NC(NCCCCCC3)=NC(NC4=CC3=CC(C(F)(F)F)=C4)=N2)=N1)(F)F
Biological Activity: IDH2R140Q-IN-1 (compound C6) is a potent inhibitor of IDH2R140Q, with an IC50 of 6.1 nM. IDH2R140Q-IN-1 can be used for the research of acute myeloid leukemia[1].
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IDH2R140Q-IN-1 | IDH2R140Q-IN-1 (compound C6) is a potent inhibitor of IDH2R140Q, with an IC50 of 6.1 nM. IDH2R140Q-IN-1 can be used for the research of acute myeloid leukemia. | |||||||||||||||||||||
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References
Keywords
