IDH2R140Q-IN-1
IDH2R140Q-IN-1 (compound C6) is a potent inhibitor of IDH2R140Q, with an IC50 of 6.1 nM. IDH2R140Q-IN-1 can be used for the research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 2469044-23-1
- Formula: C22H20F6N6
- Molecular Weight:482.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| TF-1 | IC50 |
>10 μM
Compound: C6
|
Cytotoxicity aganist human TF-1 cells harboring IDH2 mutant
Cytotoxicity aganist human TF-1 cells harboring IDH2 mutant
|
[PMID: 32679449] |
Chemical Information
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CAS No. 2469044-23-1
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Molecular Weight 482.42
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Formula C22H20F6N6
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SMILES
FC(C1=CC=CC(C2=NC(NCCCCCC3)=NC(NC4=CC3=CC(C(F)(F)F)=C4)=N2)=N1)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)