2476319-08-9
Chemical Structure
CRBN Ligand-Linker Conjugate 2
- CAS No.: 2476319-08-9
- Formula:C22H26N4O4
- Molecular Weight:410.47
SMILES: O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N(CC4)CCC54CCNCC5)=O)=O
Biological Activity: CRBN Ligand-Linker Conjugate 2 is a synthesized E3 ligand-linker conjugate that can be used for synthesis of PROTACs, such as FIP22 (HY-175764). FIP22 is a potent and selective IRAK4 PROTAC degrader with anti- atopic dermatitis activity[1].
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CRBN Ligand-Linker Conjugate 2 | CRBN Ligand-Linker Conjugate 2 is a synthesized E3 ligand-linker conjugate that can be used for synthesis of PROTACs, such as FIP22 (HY-175764). FIP22 is a potent and selective IRAK4 PROTAC degrader with anti- atopic dermatitis activity. | |||||||||||||||||||||
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Keywords