2477873-64-4
Chemical Structure
BMS-986339
- CAS No.: 2477873-64-4
- Formula:C35H41F4N3O4
- Molecular Weight:643.71
IUPAC Name: (1s,3s)-N-((4-(5-(2-fluoropropan-2-yl)-1,2,4-oxadiazol-3-yl)bicyclo[2.2.2]octan-1-yl)methyl)-3-hydroxy-N-(4'-(2-hydroxypropan-2-yl)-[1,1'-biphenyl]-3-yl)-3-(trifluoromethyl)cyclobutane-1-carboxamide
InChIKey: AEMZJBZKICOPPC-RNMMDBENSA-N
SMILES: CC(F)(C1=NC(C23CCC(CC2)(CC3)CN(C4=CC(C5=CC=C(C=C5)C(C)(O)C)=CC=C4)C([C@H]6C[C@@](O)(C6)C(F)(F)F)=O)=NO1)C
Biological Activity: BMS-986339 is an orally active, potent FXR agonist. BMS-986339 forms H-bond with His298 and ASN287 residues. BMS-986339 can be used in the research of primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH), anti-fibrosis[1].
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BMS-986339 | 99.74% | BMS-986339 is an orally active, potent FXR agonist. BMS-986339 forms H-bond with His298 and ASN287 residues. BMS-986339 can be used in the research of primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH), anti-fibrosis. | ||||||||||||||||||||
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Keywords
