2479961-46-9

RET-IN-23 Chemical Structure
2479961-46-9

Chemical Structure

RET-IN-23

  • CAS No.: 2479961-46-9
  • Formula:C28H28FN11
  • Molecular Weight:537.59

InChIKey: SYAIWXURFWCECS-UHFFFAOYSA-N

SMILES: CC1=CC(NC2=NNC(C)=C2)=NC(C3=CC=C(N4CC(C5)N(CC6=CC=C(N7C=C(F)C=N7)N=C6)C5C4)N=C3)=N1

Biological Activity: RET-IN-23 (compound 17) is a potent and orally active RET inhibitor with IC50 values of 1.32, 2.50, 6.54, 1.03, 1.47 nM for RET-WT, RET-CCDC6, RET-V804L, RET-V804M, RET-M918T, respectively. RET-IN-23 shows anti-tumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-153676
RET-IN-23 RET-IN-23 (compound 17) is a potent and orally active RET inhibitor with IC50 values of 1.32, 2.50, 6.54, 1.03, 1.47 nM for RET-WT, RET-CCDC6, RET-V804L, RET-V804M, RET-M918T, respectively. RET-IN-23 shows anti-tumor activity.
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