2479961-46-9
Chemical Structure
RET-IN-23
- CAS No.: 2479961-46-9
- Formula:C28H28FN11
- Molecular Weight:537.59
InChIKey: SYAIWXURFWCECS-UHFFFAOYSA-N
SMILES: CC1=CC(NC2=NNC(C)=C2)=NC(C3=CC=C(N4CC(C5)N(CC6=CC=C(N7C=C(F)C=N7)N=C6)C5C4)N=C3)=N1
Biological Activity: RET-IN-23 (compound 17) is a potent and orally active RET inhibitor with IC50 values of 1.32, 2.50, 6.54, 1.03, 1.47 nM for RET-WT, RET-CCDC6, RET-V804L, RET-V804M, RET-M918T, respectively. RET-IN-23 shows anti-tumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
RET-IN-23 | RET-IN-23 (compound 17) is a potent and orally active RET inhibitor with IC50 values of 1.32, 2.50, 6.54, 1.03, 1.47 nM for RET-WT, RET-CCDC6, RET-V804L, RET-V804M, RET-M918T, respectively. RET-IN-23 shows anti-tumor activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords